Rare Book Monthly

Articles - February - 2023 Issue

Google is Using Old Books and New Technology to Combat Disease

A recent story on the Google Research blog quickly caught my eye: Using new technology and old books to combat disease. We tend to think of old books as a source of information about the past, which they certainly are, but the headline indicated the people at Google Brain were using them to solve today's major problems.

 

The issue they were tackling concerned insect-borne diseases. Mosquitoes and ticks spread dangerous diseases such as malaria and lyme disease. Add to that how annoying the itching bites can be and there is good reason to seek new ways to repel these pests. The most common repellent for mosquitoes, the active ingredient in many of the repellents you find in the store, is Deet (technically, N,N-diethyl-meta-toluamide). It was discovered 80 years ago after extensive government research. However, it does have certain drawbacks, such as damaging some types of fabrics, not working with all pests, and possibly some negative effects on people.

 

What the Google researchers discovered was the government had carried on extensive testing in the 1940s when they selected Deet, but what they tested and what were the results was virtually impossible to find. It was stashed away in various places with no practical way to locate it all. However, these were Google researchers and they were aware that Google had scanned and preserved reams of this old stuff as part of Google Books. This allowed them to locate these old reports and review them. What they found was surprising. The government had tested thousands of potential repellents.

 

Exactly how Google Brain used all this data is beyond the scope of this article, which is another way of saying the computer functions and science are beyond my understanding. The computers are using AI (Artificial Intelligence) to do comparisons of promising molecules to find others that may be useful. Eventually, they came up with a list of 10 molecules that may be more effective than Deet. Further testing will be needed. Hopefully, they will find better repellents that will save lives in areas plagued by disease-bearing insects while making our picnics more pleasant.

 

The issue for us is old books, and the application of new technology to them. Google Books now has 40 million volumes scanned into their database. This is definitely the information age and that is a lot of data. The issue now is making connections, using the existing data to learn things no one realized was there, and applying it to questions we want to answer today. That is where AI comes in. It can “think” at computer speed, not human speed, and it can sort through voluminous amounts of data in split seconds. Perhaps you've had a chance to ask questions of, or even get stories or poems written on demand for you by ChatGPT. Maybe you have created some unique images through Stable Diffusion. What they can do with AI and data is astonishing, at least to those of us who grew up in the age of pencils and paper. They are fun to play around with, but as Google Brain is proving, AI is serious business. Combine it with data from old books and other sources, and there is no telling what you may discover.

 

In our own case, over the past 20 years we have put together a database of over 12.5 million records from auctions and other sources pertaining to sales of old books. It has enabled us to not only find descriptions and prices from the past, but to create a scale for estimating the current value of old prices based on an index generated strictly from book sales. We recently developed a method of using the database to estimate the value of entire collections, not just one book at a time. We can estimate how frequently a particular title is likely to come up at auction in the future. We can determine how frequently certain words are used in descriptions of a particular title. Still, there is much more to be learned, not only about books but about the interests of people at various times, and which changes predict our interests in the future. As long as the data has been accumulated, AI will enable us to learn much more than we ever dreamed possible. These are exciting times.

Rare Book Monthly

  • Heritage Auctions
    Rare Books Signature Auction
    December 15, 2025
    Heritage, Dec. 15: John Donne. Poems, By J. D. With Elegies on the Author's Death. London: M[iles]. F[lesher]. for John Marriot, 1633.
    Heritage, Dec. 15: Edgar Rice Burroughs. Tarzan of the Apes.
    Heritage, Dec. 15: F. Scott Fitzgerald. Tender is the Night. A Romance.
    Heritage, Dec. 15: Bram Stoker. Dracula. Westminster: Archibald Constable & Co., 1897.
    Heritage, Dec. 15: Jerry Thomas. How to Mix Drinks, or the Bon-Vivant's Companion, Containing Clear and Reliable Directions for Mixing All the Beverages Used in the United States…
  • Rare Book Hub is now mobile-friendly!
  • Bonhams, Dec. 8-18: Autograph Letter Signed ("Martinus Luther") to His Friend the Theologian Gerhard Wiskamp ("Gerardo Xantho Lampadario"). $100,000 - $150,000.
    Bonhams, Dec. 8-18: An Exceptionally Fine Copy of Austenís Emma: A Novel in Three Volumes. $40,000 - $60,000.
    Bonhams, Dec. 8-18: Presentation Copy of Ernest Hemmingwayís A Farewell to Arms for Edward Titus of the Black Mankin Press. $30,000 - $50,000.
    Bonhams, Dec. 8-18: Autograph Manuscript Signed Integrally for "The Songs of Pooh," by Alan Alexander. $30,000 - $50,000.
    Bonhams, Dec. 8-18: Autograph Manuscript of "Three Fragments from Gˆtterd‰mmerung" by Richard Wagner. $30,000 - $50,000.
    Bonhams, Dec. 8-18: Original Preliminary Artwork, for the First Edition of Snow Crash. $20,000 - $30,000.
    Bonhams, Dec. 8-18: Autograph Letter Signed ("T.R. Malthus") to Economist Nassau Senior on Wealth, Labor and Adam Smith. $20,000 - $30,000.
    Bonhams, Dec. 8-18: History of the Peloponnesian War by Thucydides Finely Bound by Michael Wilcox. $20,000 - $30,000.
    Bonhams, Dec. 8-18: First Edition of Lewis and Clark: Travels to the Source of the Missouri River and Across the American Continent to the Pacific Ocean. $8,000 - $12,000.
    Bonhams, Dec. 8-18: Original Artwork for the First Edition of Neal Stephenson's Groundbreaking Novel Snow Crash. $100,000 - $150,000.
    Bonhams, Dec. 8-18: A Complete Set Signed Deluxe Editions of King's The Dark Tower Series by Stephen King. $8,000 - $12,000.
    Bonhams, Dec. 8-18: Autograph Letter Signed ("John Adams") to James Le Ray de Chaumont During the Crucial Years of the Revolutionary War. $8,000 - $12,000.
  • Sotheby’s
    Book Week
    December 9-17, 2025
    Sotheby’s, Dec. 17: Francesco Colonna. Hypnerotomachie, Paris, 1546, Parisian calf by Wotton Binder C for Marcus Fugger. €200,000 to €300,000.
    Sotheby’s, Dec. 17: Nausea. De principiis dialectices Gorgias, and other works, Venice, 1523, morocco gilt for Cardinal Campeggio. €3,000 to €4,000.
    Sotheby’s, Dec. 17: Billon. Le fort inexpugnable de l'honneur, Paris, 1555, Parisian calf gilt for Peter Ernst, Graf von Mansfeld. €120,000 to €180,000.
    Sotheby’s
    Book Week
    December 9-17, 2025
    Sotheby’s, Dec. 16: Salinger, J.D. The Graham Family archive, including autographed letters, an inscribed Catcher, a rare studio photograph of the author, and more. $120,000 to $180,000.
    Sotheby’s, Dec. 16: [Austen, Jane]. A handsome first edition of Sense and Sensibility, the author's first novel. $60,000 to $80,000.
    Sotheby’s, Dec. 16: Massachusetts General Court. A powerful precursor to the Declaration of Independence: "every Act of Government … without the Consent of the People, is … Tyranny." $40,000 to $60,000.

Article Search

Archived Articles